Thermo Fisher Scientific Inc. is the world leader in serving science, with revenues of $30 billion and approximately 80,000 employees globally. Our Mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics, deliver medicines to market and increase laboratory productivity.
Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services – we offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive services.
The successful candidate will be joining Bangalore R&D leadership team in developing products and solutions for developing, validating and characterizing Antibodies for Thermo Fisher Antibody portfolio. The candidate should be well versed with Antibody development using state-of-art cell, molecular biology, recombinant methods for creating data sets to enable high quality products to customers. This position involves cross functional collaboration internal and external to drive technical strategies for execution in R&D projects involving state-of-art methods including western blotting, chromatin immunoprecipitation (ChIP), RNA immunoprecipitation (RIP), Antibody engineering, protein conjugation and flow applications.
Role & Responsibilities
Contribute in a fast- paced environment towards Antibody development & Validation
R&D Manager role in new Antibody development projects with vast experience in experimental planning and execution to meet the program milestone.
Lead team of scientists in matrix style operation, provide technical and operational supervision.
Good scientific writing skills, establishing technical protocols for effective transfer to operation teams.
Mentoring and training junior scientists in research, designing and experimental execution, interpreting data and data presentation to the stakeholders.
Good documentation practice is a must to maintain data integrity and accuracy.
Delivering high quality results according to project schedule in support of product commercialization from concept to launch including early feasibility, development and validation phases.
Support manufacturing team for technical support and quality by providing technical guidance.
Skills and Experience
Experience in the field of molecular biology, protein expression, protein purification, and protein-protein interaction.
Experience in applying scientific principles and concepts in antibody development platforms with knowledge of emerging technologies such as deep sequencing or mining of antibody repertoires using NGS, phage or cell display, affinity maturation etc. Spatial omics knowledge is a plus.
Familiarity or experience in antibody engineering, computational tools for antibody modeling and rational design.
Expertise in development of conjugation chemistries or performing antibody conjugations.
Ability to provide technical trouble shooting to resolve scientific problems.
Proficient in software or platforms for molecular biology and sequence analysis, MS Office and statistic software such as GraphPad Prism.
Authorship of peer-reviewed publications with post-doctoral experience and a strong, independent understanding of standard and emerging research protocols and techniques are preferred. GLP experience is a must.
Ph.D in Biotechnology/Life Sciences or related discipline or Masters in cell biology/biotechnology, genetics or related fields with at least 10+ years of relevant experience